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Figure 2: Neurocircuitry in major depressive disorder (MDD): In this figure, complex analyses based upon functional neuroimaging can determine not only which specific neuroanatomic areas are hyper or hypofunctional in the MDD patient, but further analyses the strength, or weakness, in the connectivity between brain regions. This may help delineate MDD from control subjects and possibly determine which brain endophenotypic findings need to be remedied to alleviate symptoms (Zeng et al., 2012.[32] Reproduced with permission obtained by author.)

Figure 2: Neurocircuitry in major depressive disorder (MDD): In this figure, complex analyses based upon functional neuroimaging can determine not only which specific neuroanatomic areas are hyper or hypofunctional in the MDD patient, but further analyses the strength, or weakness, in the connectivity between brain regions. This may help delineate MDD from control subjects and possibly determine which brain endophenotypic findings need to be remedied to alleviate symptoms (Zeng <i>et al.</i>, 2012.<sup>[32]</sup> <i>Reproduced with permission obtained by author.)</i>